Calcium Chondroitin Sulfate, CDS, Chondroitin, Chondroitin Polysulfate, Chondroitin Polysulphate, Chondroitin Sulfate A, Chondroitin Sulfates, Chondroitin Sulfate B, Chondroitin Sulfate C, Chondroitin Sulphates, Chondroitin Sulphate A Sodium, Chondroïtine, Chondroïtine Sulfate A, Chondroïtine Sulfate B, Chondroïtine Sulfate C, Chondroïtine 4-sulfate, Chondroïtine 4- et 6- sulfate, Condroitin, CPS, CS, CSA, CSC, GAG, Galactosaminoglucuronoglycan Sulfate, Chondroitin 4-sulfate, Chondroitin 4- and 6-sulfate, Poly-(1->3)-N-aceltyl-2-amino-2-deoxy-3-O-beta-D-glucopyranurosyl-4-(or 6-), Polysulfate de Chondroïtine, Sulfate de Chondroïtine, Sulfate de Galactosaminoglucuronoglycane, Sulfates de Chondroïtine, Sulfato de Condroitina.

Chondroitin sulfate is a chemical that is normally found in cartilage around joints in the body. Chondroitin sulfate is usually manufactured from animal sources, such as shark and cow cartilage. It can also be made in a lab.

Some chondroitin sulfate products are not labeled accurately. In some cases, the amount of chondroitin has varied from none to more than 100% of the amount stated on the product's label. Also, some products contain chondroitin that is taken from multiple different animals, even though this is not always stated on the label.

Chondroitin sulfate is used for osteoarthritis and cataracts. It is often used in combination with other ingredients, including manganese ascorbate, hyaluronic acid, collagen peptides, or glucosamine. Chondroitin sulfate is also taken by mouth, applied to the skin, and given as a shot for many other conditions, but there is no good scientific evidence to support these uses.

How does it work?

In osteoarthritis, the cartilage in the joints breaks down. Taking chondroitin sulfate, one of the building blocks of cartilage, might slow this breakdown.

Side Effects & Safety

When taken by mouth: Chondroitin sulfate is LIKELY SAFE. Chondroitin sulfate has been taken by mouth safely for up to 6 years. It can cause some mild stomach pain and nausea. Other side effects that have been reported are bloating, diarrhea, constipation, headache, swollen eyelids, leg swelling, hair loss, skin rash, and irregular heartbeat.

When placed into the eye: Chondroitin sulfate is LIKELY SAFE when used as an eye solution during cataract surgery.

When given as a shot: Chondroitin sulfate is POSSIBLY SAFE when injected into the muscle as a shot, short-term.

There is some concern about the safety of chondroitin sulfate because it comes from animal sources. Some people are worried that unsafe manufacturing practices might lead to contamination of chondroitin products with diseased animal tissues, including those that might transmit bovine spongiform encephalopathy (mad cow disease). So far, there are no reports of chondroitin causing disease in humans, and the risk is thought to be low.

Some chondroitin products contain excess amounts of manganese. Ask your healthcare professional about reliable brands.

Special Precautions & Warnings:

Pregnancy and breast-feeding: There isn't enough reliable information to know if chondroitin sulfate is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.

Asthma: There is some concern that chondroitin sulfate might make asthma worse. If you have asthma, use chondroitin sulfate cautiously.

Blood clotting disorders: In theory, administering chondroitin sulfate might increase the risk of bleeding in people with blood clotting disorders.

Prostate cancer: Early research suggests that chondroitin might cause the spread or recurrence of prostate cancer. This effect has not been shown with chondroitin sulfate supplements. However, until more is known, do not take chondroitin sulfate if you have prostate cancer or are at high risk for developing it (you have a brother or father with prostate cancer).

Warfarin (Coumadin) interacts with CHONDROITIN SULFATE

 

Warfarin (Coumadin) is used to slow blood clotting. There are several reports showing that taking chondroitin with glucosamine increases the effect of warfarin (Coumadin) on blood clotting. This can cause bruising and bleeding that can be serious. Don't take chondroitin if you are taking warfarin (Coumadin).

Dosing

The following doses have been studied in scientific research:

BY MOUTH:

  • For osteoarthritis: The typical dose of chondroitin sulfate is 800-2000 mg taken as a single dose or in two or three divided doses daily for up to 3 years.

APPLIED TO THE SKIN:

  • For osteoarthritis: A cream containing 50 mg/gram of chondroitin sulfate, 30 mg/gram of glucosamine sulfate, 140 mg/gram of shark cartilage, and 32 mg/gram of camphor has been used as needed for sore joints for up to 8 weeks.

INJECTED INTO THE MUSCLE:

  • For osteoarthritis: Chondroitin sulfate (Matrix) has been injected into the muscle daily or twice weekly for 6 months.

APPLIED TO THE EYE:

  • For cataracts: Several different eye drops containing sodium hyaluronate and chondroitin sulfate (DisCoVisc, Alcon Laboratories; Viscoat, Alcon Laboratories; DuoVisc, Alcon Laboratories; Viscoat, Alcon Laboratories; Provisc, Alcon Laboratories) have been used during cataract surgery.
  • Overall User Ratings

    17 Total User Reviews

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    Effectiveness

    Current Rating: 0

    (3.27)

    Ease of Use

    Current Rating: 0

    (4.09)

    Satisfaction

    Current Rating: 0

    (2.82)

    User Reviews 

     
    1-5 of 11 Next»
    Reason for taking: Arthritis
    10/31/2019 8:20:19 PM

    Reviewer: Mike, 75 or over Male on Treatment for 1 to 6 months (Consumer)

     

    Effectiveness

    Current Rating: 1

    Ease of Use

    Current Rating: 5

    Satisfaction

    Current Rating: 1

    Comment:
    Absolutely no effect. I'm 85 and have some arthritis in my thumb joints. Only using this since my caring daughter decided I should! Waste of time and her money.

    Reason for taking: Arthritis
    12/9/2017 12:28:49 PM

    Reviewer: violeta, 55-64 Female on Treatment for 1 to 6 months (Consumer)

     

    Effectiveness

    Current Rating: 3

    Ease of Use

    Current Rating: 5

    Satisfaction

    Current Rating: 3

    Comment:

    Reason for taking: Arthritis
    11/14/2016 8:05:04 AM

    Reviewer: Rejoint, 55-64 on Treatment for 5 to less than 10 years (Consumer)

     

    Effectiveness

    Current Rating: 4

    Ease of Use

    Current Rating: 4

    Satisfaction

    Current Rating: 4

    Comment:
    i have been taking Glucosamine sulphate and chodrotin sulphate supplements for the last six years for osteoarthritis. when i started the tablet i was in serious condition of not being able to walk with pain even for 5 minutes. After three - four years of use only the tablet started working for me.. now i can walk upto half an hour without any pain...i was limping earlier even 3-4 years ago and now my walking is quite normal... rarely i have pain in the knee, that too if i walk for more than 2 km.
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    Reason for taking: Arthritis
    3/1/2016 10:47:57 AM

    Reviewer: farmacista, 75 or over on Treatment for 5 to less than 10 years (Consumer)

     

    Effectiveness

    Current Rating: 3

    Ease of Use

    Current Rating: 3

    Satisfaction

    Current Rating: 3

    Comment:
    no cartilage repaired

    Reason for taking: Arthritis
    12/15/2014 10:10:08 AM

    Reviewer: Jmc, 65-74 Female (Consumer)

     

    Effectiveness

    Current Rating: 5

    Ease of Use

    Current Rating: 5

    Satisfaction

    Current Rating: 5

    Comment:
    Have less knee discomfort,have been taking for over 10 years.have taken various strengths and combinations (double,triple,MSM etc.)